Course syllabus

Course-PM

KBT221 Radiopharmaceutical chemistry lp1 HT19 (7.5 hp)

Course is offered by the department of Chemistry and Chemical Engineering, Nuclear Chemistry and Industrial Materials Recycling, Floor 6, Research House 2

Contact details

Examiner: Assoc. Prof. Teodora Retegan Vollmer, tretegan@chalmers.se, +317722881

Lab Supervisor: Dr. Emma Aneheim (GU)

Lecturer: Assoc. Prof. Store Lindegren (GU)

Course purpose

The course will focus on interaction of radiation with matter, micro dosimetry, radionuclide production, radionuclide generators, design of a radiopharmacy lab, how to work in a radiopharmacy lab, radiolabelling, quality control, factors which affect the integrity of radiopharmaceuticals, legislation, practical issues (documentation, labeling, transport, etc), waste management in radiopharmacy, pharmacology, pharmacokinetics and metabolism of radiopharmaceuticals, diagnostic and therapeutic applications, PET and heavy ion therapy.

The course consists of a series of lectures, a laboratory project as well as a study visit to the pharmaceutical research facility of the company AstraZeneca, Mölndal.

Schedule

TimeEdit

Course literature

Charles B. Sampson “Textbook of Radiopharmacy – Theory and Practice, 2nd enlarged edition”, Gordon and Breach Publishers, or other editions as well (in English) 

Course design

The course consists of a series of lectures, a laboratory project at Shalgrenska University Hospital as well as a study visit to the pharmaceutical research facility of the company Astra Zeneca, Mölndal.

Provide a plan for

• lectures - will be provided during established time and dates
• laboratory work - will be performed at Shalgrenska, 2 groups 
• supervision - will be continuous through dialog or messages
• feedback - laboratory feedback will be provided by laboratory supervisor

Changes made since the last occasion

The lectures and laboratory are updated compared to 2018 with new information and up-to-date facts

Learning objectives and syllabus

The aim of the course is to:

• give broad information about the use of radioactive nuclides in nuclear medicine;
• give information about the use of radionuclides for diagnosis and therapy;
• give information about the production and properties of radionuclides used for medical purposes;
• give information about the synthesis of radiolabelled compounds;
• give information about production and test of radiopharmaceuticals;
• teach practical labeling work.

At the end of the course, the students should have an understanding of:

• the use of radioactive nuclides in nuclear medicine;

• the use of radionuclides for diagnosis and therapy
;
• the production and properties of radionuclides used for medical purposes;
• the synthesis of radiolabelled compounds;
• the production and test of radiopharmaceuticals;
• to perform practical labeling work.

Link to the syllabus on Studieportalen.

Study plan

Examination form

The examination will be a written exam, containing questions from the provided material, including  the laboratory exercise. Older exams are provided.

In order to be able to attend the exam, you must pass the laboratory exercise and participate to 60% of the lectures. The laboratory is compulsory.

Study Tour

Study tour is optional, however is recommended, since it shows a real facility site and gives the opportunity to network with industry.

Please sign-up for the visit in good time

Description of how the examination – written examinations and other – is executed and assessed.